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Lymphotoxin β Receptor Induces Interleukin 8 Gene Expression via NF-κB and AP-1 Activation

✍ Scribed by Ying-Hsin Chang; Shie-Liang Hsieh; Mei-Chieh Chen; Wan-Wan Lin


Book ID
115604328
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
195 KB
Volume
278
Category
Article
ISSN
0014-4827

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## Abstract Lymphotoxin beta receptor (LTβR) activation on mouse fibrosarcoma cells (BFS‐1) results in enhanced solid tumor growth paralleled by increased angiogenesis induced by the expression of pro‐angiogenic CXCL2. In our study, we demonstrate that both functional ligands of the LTβR, namely LT