Lymphokine-activated killer-cell traffic in metastatic melanoma
✍ Scribed by Dummer, R; Schäfer, E; Eilles, C; Börner, W; Burg, G
- Book ID
- 123117816
- Publisher
- The Lancet
- Year
- 1991
- Tongue
- English
- Weight
- 377 KB
- Volume
- 338
- Category
- Article
- ISSN
- 0140-6736
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Adoptive transfer of autologous lymphokine-activated killer cells (LAK) in conjunction with recombinant interleukin-2 (rIL-2) has been reported to produce significant regression in metastatic disease in patients with advanced cancer. In an effort to confirm the results reported by the Surgery Branch
Lymphokine-activated killer cells were generated from peripheral blood mononuclear cells of 33 patients with liver tumors (benign, 6; primary malignant, 10; metastatic, 17) and 10 healthy individuals. Although peripheral blood mononuclear cell yield was significantly lower (p < 0.01) in patients wit