Lymphokine-activated killer cell activity
โ Scribed by Dwain L. Thiele; Peter E. Lipsky
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 147 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0167-5699
No coin nor oath required. For personal study only.
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Natural killer (NK) cells and lymphokine-activated killer (LAK) cells are anomalous cytotoxic cells which are potentially important in host defense against cancer. Several studies have demonstrated that natural killer (NK) cell activity can be suppressed by chemical inhibitors of the lipoxygenase pa
Lymphokine-activated killer cells were generated from peripheral blood mononuclear cells of 33 patients with liver tumors (benign, 6; primary malignant, 10; metastatic, 17) and 10 healthy individuals. Although peripheral blood mononuclear cell yield was significantly lower (p < 0.01) in patients wit