Lymphoid chemokines in chronic neuroinflammation
β Scribed by Francesca Aloisi; Sandra Columba-Cabezas; Diego Franciotta; Barbara Rosicarelli; Roberta Magliozzi; Richard Reynolds; Elena Ambrosini; Eliana Coccia; Marco Salvetti; Barbara Serafini
- Book ID
- 113730288
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 350 KB
- Volume
- 198
- Category
- Article
- ISSN
- 0165-5728
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Neuroinflammation has been implicated recently in the pathogenesis of many neurodegenerative diseases. The cross-talk between neurons and non-neuronal cells seems to be a critical step in the progression of neurodegeneration and molecules that have a beneficial role may turn into harmful players. Th
Leukocytes respond to complex patterns of chemoattractant cytokine (chemokine) gradients that guide them to their destinations in secondary lymphoid organs. This directed movement of multiple cell types requires the choreographed expression of specific G-protein-coupled chemokine receptors and both