๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Chemokine receptors in lymphoid organ homeostasis

โœ Scribed by Steffen Jung; Dan R Littman

Book ID
104359095
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
758 KB
Volume
11
Category
Article
ISSN
0952-7915

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โœฆ Synopsis

Leukocytes respond to complex patterns of chemoattractant cytokine (chemokine) gradients that guide them to their destinations in secondary lymphoid organs. This directed movement of multiple cell types requires the choreographed expression of specific G-protein-coupled chemokine receptors and both positive and negative regulation of the signal transduction pathways emanating from them.

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โœ Noah P. Zimmerman; Rebecca A. Vongsa; Michael K. Wendt; Michael B. Dwinell ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 289 KB

Chemokines, a large family of small chemoattractive cytokines, and their receptors play an integral role in the regulation of the immune response and homeostasis. The ability of chemokines to attract specific populations of immune cells sets them apart from other chemoattractants. Chemokines produce