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Lymphocyte mitogenesis induced by monoclonal antibodies to the T3 complex. Differential modulation by human IgG

✍ Scribed by Constantine D. Tsoukas; John Lambris; Martin Lotz; Mary A. Valentine; John H. Vaughan; Dennis A. Carson


Book ID
113132953
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
621 KB
Volume
89
Category
Article
ISSN
0008-8749

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Human in vivo antigenic modulation induc
✍ Lucienne Chatenoud; Marc F. Baudrihaye; Henri Kreis; Gideon Goldstein; John Schi πŸ“‚ Article πŸ“… 1982 πŸ› John Wiley and Sons 🌐 English βš– 345 KB

## Abstract The anti‐pan T cell monoclonal antibody OKT3 was administered daily for 2 weeks in four human renal allograft recipients. The antibody induced a dramatic and immediate depletion of peripheral T cells followed by an __in vivo__ antigenic modulation of the OKT3‐defined membrane antigen: a