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Lymphoblastoid interferon alfa with or without steroid pretreatment in children with chronic hepatitis B: A multicenter controlled trial

✍ Scribed by GV Gregorio; P Jara; L Hierro; C Diaz; A de la Vega; A Vegnente; R Iorio; F Bortolotti; C Crivellaro; L Zancan; H Daniels; B Portmann; G Mieli-Vergani


Book ID
118686199
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
206 KB
Volume
23
Category
Article
ISSN
0270-9139

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Lymphoblastoid interferon alfa with or w
✍ G V Gregorio; P Jara; L Hierro; C Diaz; A de la Vega; A Vegnente; R Iorio; F Bor πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 202 KB πŸ‘ 1 views

## Steroid priming does not potentiate the effect of IFN-a. The comparative efficacy of prednisolone followed by (HEPATOLOGY 1996;23:700-707.) interferon alfa (IFN-a) versus IFN-a alone in enhancing the rate of antibody to hepatitis B e antigen (anti-HBe) seroconversion has not been evaluated in a

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Ongoing hepatitis B virus replication in the presence of antibody to HBeAg can be observed in patients with active liver disease. These forms of chronic hepatitis B have been described as having a poor prognosis. We have conducted a randomized controlled trial to assess the efficacy of lymphoblastoi

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Thirty-six children with chronic hepatitis B were entered into a randomized controlled trial of recombinant human interferon-a. All patients had hepatitis B virus DNA and increased levels of aminotransferases in serum for at least 1 yr. Twelve children received 10 MU of interferon-a 2b/m2 body surfa