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Lymphatic transport of cholesterol in normocholesterolemic rats treated with pravastatin, an inhibitor of HMG-CoA reductase

โœ Scribed by Masanobu Sakono; Toko Ibi; Koji Nagao; Ikuo Ikeda; Kyosuke Yamamoto; Katsumi Imaizumi


Book ID
118326373
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
647 KB
Volume
124
Category
Article
ISSN
0021-9150

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Disposition of fluvastatin, an inhibitor
โœ F. L. S. Tse; H. T. Smith; F. H. Ballard; J. Nicoletti ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 579 KB

The physiological disposition offluvastatin, a potent inhibitor of hydroxymethylglutaryl-CoA reductase and thus cholesterol synthesis, has been studied in the mouse, rat, dog, and monkey using 14C-or 3H-labeled drug. Oral doses of fluvastatin were absorbed at a moderate to rapid rate. The extent of