Lycodine-Type Alkaloids from Lycopodium casuarinoides

✍ Scribed by Sheng Yin; Cheng-Qi Fan; Xiao-Ning Wang; Jian-Min Yue

• Book ID: 102253299
• Publisher: John Wiley and Sons
• Year: 2006
• Tongue: German
• Weight: 122 KB
• Volume: 89
• Category: Article
• ISSN: 0018-019X
• DOI: 10.1002/hlca.200690006

✦ Synopsis

Two new lycodine-type alkaloids, huperzinine N-oxide (1) and 8,15-dihydrohuperzinine (2) as well as five known compounds, huperzinine (3), huperzine B (4), huperzine D (5), N-demethylhuperzinine (6), and b-obscurine (7), were isolated from the club moss Lycopodium casuarinoides. The structures of 1 and 2 were elucidated by spectroscopic methods and chemical transformation. The absolute configuration of 1 was established by chemical correlation with 3, and that of 2 was determined by its CD spectrum.