LRRK2 Pro755Leu variant in ethnic Chinese population with Parkinson's disease
β Scribed by Ling-yan Yao; Ji-feng Guo; Lei Wang; Ren-he Yu; Qi-ying Sun; Qian Pan; Kun Xia; Bei-sha Tang; Lu Shen
- Book ID
- 116773065
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 305 KB
- Volume
- 495
- Category
- Article
- ISSN
- 0304-3940
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π SIMILAR VOLUMES
## Abstract A heterozygous 2264CβT variant (P755L) in __LRRK2__ gene has been reported to be a likely pathogenic variant among ethnic Chinese patients with Parkinson's disease (PD). In a case control study, we performed genetic analysis of the P755L variant in an independent cohort of Chinese patie
## Abstract We conducted a caseβcontrol study to determine the prevalence of the __LRRK2__ Gly2385Arg variant in patients with Parkinson's disease in Han population in mainland China. Heterozygous __LRRK2__ Gly2385Arg variant was identified in 14 of 235 patients with Parkinson's disease (5.69%), bu