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LRRK2, a puzzling protein: Insights into Parkinson's disease pathogenesis

✍ Scribed by Esteves, A. Raquel; Swerdlow, Russell H.; Cardoso, Sandra M.

Book ID
124107734
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
872 KB
Volume
261
Category
Article
ISSN
0014-4886

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Leucine-rich repeat kinase 2 (LRRK2): A
Leucine-rich repeat kinase 2 (LRRK2): A key player in the pathogenesis of Parkinson's disease
✍ Payal N. Gandhi; Shu G. Chen; Amy L. Wilson-Delfosse πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 209 KB

## Abstract Parkinson's disease (PD) is the most common neurodegenerative movement disorder, with a prevalence of more than 1% after the age of 65 years. Mutations in the gene encoding leucine‐rich repeat kinase‐2 (__LRRK2__) have recently been linked to autosomal dominant, late‐onset PD that is cl