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LOX-1 expressed in cultured rat chondrocytes mediates oxidized LDL-induced cell death—possible role of dephosphorylation of Akt

✍ Scribed by Takefumi Nakagawa; Tadashi Yasuda; Hajime Hoshikawa; Makoto Shimizu; Takumi Kakinuma; Mingyi Chen; Tomoh Masaki; Takashi Nakamura; Tatsuya Sawamura

Book ID: 117052874
Publisher: Elsevier Science
Year: 2002
Tongue: English
Weight: 293 KB
Volume: 299
Category: Article
ISSN: 0006-291X
DOI: 10.1016/s0006-291x(02)02597-4

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## Abstract Oxidative stress, the result of cellular production of reactive oxygen species (ROS), has been implicated in causing many renal diseases. Adenosine triphosphate (ATP) is an important extracellular signal in the regulation of many intracellular processes in normal tubular cells as well a