Lowering the sensitivity of cholecystokinin receptors in the brain by chronic haloperidol administration
โ Scribed by E. E. Vasar; A. H. Soosaar; M. O. Maimets; L. H. Allikmets
- Publisher
- Springer US
- Year
- 1986
- Tongue
- English
- Weight
- 316 KB
- Volume
- 102
- Category
- Article
- ISSN
- 0007-4888
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Rats received haloperidol (1.3-1.5 mg/kg/day) via their drinking water for 21 weeks. At the end of this period the density of D2 dopamine receptors and their affinity for [3H]-spiperone were measured in the striatum and medial prefrontal cortex. The chronic haloperidol treatment increased the densit