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Lower mutation frequencies are induced by ENU in undifferentiated embryonic cells than in differentiated cells of the mouse in vitro

✍ Scribed by Ulrich Sehlmeyer; Anna M. Wobus


Book ID
113255904
Publisher
Elsevier Science
Year
1994
Weight
621 KB
Volume
324
Category
Article
ISSN
0165-7992

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## Abstract Recently it was shown that embryonic stem (ES) cells could differentiate into hepatocytes both in vitro and in vivo, however, prospective hepatic progenitor cells have not yet been isolated and characterized from ES cells. Here we presented a novel 4‐step procedure for the differentiati