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Higher induction of mutations and micronuclei by MNNG and mitomycin C in differentiated than in undifferentiated cells of the mouse in vitro

โœ Scribed by U. Sehlmeyer; W. Beisker; A.M. Wobus


Book ID
114133409
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
83 KB
Volume
360
Category
Article
ISSN
0165-1161

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The sensitivity to sister chromatid exchange (SCE) induction by N-methyl-nitro-N'-nitrosoguanidine (MNNG) in human, mouse, Chinese hamster, and Syrian hamster normal cell strains and in permanent transformed cell lines of the same species was compared. Exponentially growing or growth-inhibited cultu