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Low-valent titanium induced reductive cyclization of nitro compounds and aliphatic ketones: facile synthesis of 3, 4-dihydro(2H)-1, 2, 4-benzothiadiazine-1, 1-dioxides

โœ Scribed by Wei-Hui Zhong; Xiao-Yuan Chen; Yong-Min Zhang


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
178 KB
Volume
18
Category
Article
ISSN
0256-7660

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## Abstract A new method for the preparation of 4โ€substituted 3,4โ€dihydroโ€1__H__โ€2,1,3โ€benzothiadiazine 2,2โ€dioxides is described. Treatment of __t__โ€butyl __N__โ€phenylsulfamoylcarbamate derivatives (**1**) with different aldehydes afforded the corresponding intramolecular cyclized products **2** u