Low-Molecular-Weight Enzyme Inhibitors of Microbial Origin
β Scribed by Umezawa, Hamao
- Book ID
- 111866790
- Publisher
- Annual Reviews
- Year
- 1982
- Tongue
- English
- Weight
- 807 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0066-4227
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A crude preparation, inhibiting trypsin (T), chymotrypsin (C) and papain (P), was isolated from the culture filtrate of Actinomyces sp. 9 by butanol extraction. Ion-exchange high-performance liquid chromatography (HPLC) of this preparation on a Mono S column resulted in the separation of two inhibit
## Abstract **Summary:** Lowβmolecularβweight poly(__Ξ±__βmethyl __Ξ²__,Lβmalate) made of approximately 25β30 units was prepared from microbial poly(__Ξ²__,Lβmalic acid) by treatment with diazomethane. The thermal characterization of the polymalate methyl ester was carried out and its crystalline stru