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Low microsatellite instability and high loss of heterozygosity rates indicate dominant role of the suppressor pathway in squamous cell carcinoma of head and neck and loss of heterozygosity of 11q14.3 correlates with tumor grade

✍ Scribed by Damjan Glavač; Metka Volavšek; Uroš Potočnik; Metka Ravnik-Glavač; Nina Gale


Book ID
114135633
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
281 KB
Volume
146
Category
Article
ISSN
0165-4608

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Microsatellite instability and loss of h
✍ Susanne Koy; Jens Plaschke; Hella Luksch; Katrin Friedrich; Eberhard Kuhlisch; U 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 842 KB

## Abstract ## Background. Microsatellite instability (MSI) in head and neck squamous cell carcinoma (HNSCC) has been reported with a wide range of frequencies. The aim of our study was to disclose the frequency and basis of MSI in HNSCC and to correlate MSI and findings on loss of heterozygosity