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Low frequency of mtDNA point mutations in patients with PEO associated with POLG1 mutations

✍ Scribed by Kollberg, Gittan; Jansson, Monica; Pérez-Bercoff, Åsa; Melberg, Atle; Lindberg, Christopher; Holme, Elisabeth; Moslemi, Ali-Reza; Oldfors, Anders


Book ID
110026146
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
212 KB
Volume
13
Category
Article
ISSN
1018-4813

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## Communicated by Riccardo Fodde Familial adenomatous polyposis has been linked to germline mutations in the APC tumor suppressor gene. However, a number of patients with familial adenomatous polyposis (with either classical or attenuated phenotype) have no APC mutation. Recently, germline mutatio