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Low doses of reactive oxygen species protect endothelial cells from apoptosis by increasing thioredoxin-1 expression

✍ Scribed by Judith Haendeler; Verena Tischler; Jörg Hoffmann; Andreas M. Zeiher; Stefanie Dimmeler


Book ID
116465008
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
262 KB
Volume
577
Category
Article
ISSN
0014-5793

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Intracellular reactive oxygen species (ROS) may participate in cellular responses to various stimuli including hemodynamic forces and act as signal transduction messengers. Human umbilical vein endothelial cells (ECs) were subjected to laminar shear flow with shear stress of 15, 25, or 40 dynes/cm 2