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Low-dose thalidomide in combination with oral fludarabine and cyclophosphamide is ineffective in heavily pretreated patients with chronic lymphocytic leukemia

✍ Scribed by Krzysztof Giannopoulos; Anna Dmoszyńska; Jacek Roliński

Book ID
104040250
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
192 KB
Volume
31
Category
Article
ISSN
0145-2126

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Low-dose oral fludarabine plus cyclophos
Low-dose oral fludarabine plus cyclophosphamide in elderly patients with untreated and relapsed or refractory chronic lymphocytic Leukaemia
✍ Francesco Forconi; Alberto Fabbri; Mariapia Lenoci; Elisa Sozzi; Alessandro Gozz 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 163 KB

## Abstract Fludarabine plus cyclophosphamide (FC) at conventional doses is an effective treatment for chronic lymphocytic leukaemia (CLL). However, FC at standard doses may give hematological and non‐hematological toxicity, predominantly in the elderly. Intravenous or oral low‐dose FC regimens rem