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Low-dose thalidomide in combination with oral fludarabine and cyclophosphamide is ineffective in heavily pre-treated patients with chronic lymphocytic leukemia

โœ Scribed by Luca Laurenti; Paola Piccioni; Michela Tarnani; Laura De Padua; Mariagrazia Garzia; Dimiter G. Efremov; Nicola Piccirillo; Patrizia Chiusolo; Simona Sica; Giuseppe Leone


Book ID
104040185
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
99 KB
Volume
31
Category
Article
ISSN
0145-2126

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Low-dose oral fludarabine plus cyclophos
โœ Francesco Forconi; Alberto Fabbri; Mariapia Lenoci; Elisa Sozzi; Alessandro Gozz ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 163 KB

## Abstract Fludarabine plus cyclophosphamide (FC) at conventional doses is an effective treatment for chronic lymphocytic leukaemia (CLL). However, FC at standard doses may give hematological and nonโ€hematological toxicity, predominantly in the elderly. Intravenous or oral lowโ€dose FC regimens rem