Genetic factors play a major role in the etiology of idiopathic generalized epilepsy. However, in most syndromes, especially the common ones, multiple genetic factors seem to be involved. Mutations in K + channel genes have previously found to be associated with epilepsy both in humans and in mice.
Low dose sodium valproate in the treatment of juvenile myoclonic epilepsy
β Scribed by Anna Karlovassitou-Koniari; Dimitra Alexiou; Petros Angelopoulos; Pantelis Armentsoudis; Evangelia Dimitrakoudi; Ioannis Delithanasis; Paris Hamlatzis; Stavros Baloyannis
- Publisher
- Springer
- Year
- 2002
- Tongue
- English
- Weight
- 149 KB
- Volume
- 249
- Category
- Article
- ISSN
- 0340-5354
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The acute effect of oral administration of a single dose of vigabatrin, a new antiepileptic drug which acts by irreversible enzyme-activated inhibition of the brain enzyme, GABA-aminotransferase, on the photoconvulsive response in patients with photosensitive epilepsy, was compared with that of the
## Objectives: The efficacy and tolerability of sodium valproate 2 x 240 mg compared to placebo were investigated in aggressive behavior in dementia. ## Design: A randomized, placebo controlled, double-blind cross-over design. the trial included a baseline period (one week); a placebo period (thr