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Low dose fibroblast growth factor-2 (FGF-2) enhances bone morphogenetic protein-2 (BMP-2)-induced ectopic bone formation in mice

✍ Scribed by Yukio Nakamura; Keiji Tensho; Hiroyuki Nakaya; Masashi Nawata; Takahiro Okabe; Shigeyuki Wakitani

Book ID: 116319096
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 566 KB
Volume: 36
Category: Article
ISSN: 8756-3282
DOI: 10.1016/j.bone.2004.11.010

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## Abstract Bone morphogenetic proteins (BMP) stimulate osteoblast differentiation by signal transduction via three BMP receptors (BMPR‐IA, ‐IB, and ‐II). Several growth factors, including transforming growth factor‐β1 (TGF‐β1), fibroblast growth factor‐2 (FGF‐2) and platelet‐derived growth factor‐