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Low dose cytosine arabinoside (Ara C) in myelodysplastic syndromes

✍ Scribed by G. Tricot; R. De Bock; A. W. Dekker; M. A. Boogaerts; M. Peetermans; K. Punt; R. L. Verwilghen


Book ID
114710327
Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
512 KB
Volume
58
Category
Article
ISSN
0007-1048

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## Abstract Four patients with non‐Hodgkin lymphoma and two with acute lymphocytic leukemia (ages 4 years 4 months to 16 years 6 months) exhibited a unique reaction to intravenously administered cytosine arabinoside (Ara‐C) given alone as a part of the previously reported LSA~2~‐L~2~ treatment prot

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Seven patients with a myelodysplastic syndrome or "smoldering" acute myelogenous leukemia were treated with cytosine arabinoside in low dosage. Four patients experienced transient, partial responses characterized by improved peripheral blood counts, cessation of transfusion requirements, and a decre