Background. The response rate of metastatic renal cell cancer to cytotoxic therapy over the last 10 years has been 5.6%. Low dose continuous 5-fluorouracil(5-FU) has demonstrated efficacy in other cytotoxic refractory tumors, such as pancreas, colorectal, and recurrent breast. The Southwest Oncology
Low-dose continuous infusion 5-fluorouracil. Evaluation in advanced breast carcinoma
β Scribed by Susan Huan; Richard Pazdur; Amnuay Singhakowinta; Bohumil Samal; Vainutis K. Vaitkevicus
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- English
- Weight
- 363 KB
- Volume
- 63
- Category
- Article
- ISSN
- 0008-543X
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City Uni-11 cases, for an overall response rate of 50%. Patients with good performance versity Medical School, Osaka, Japan. status (PS) (0-1) and differentiated histologic type showed higher response rates (50.0% and 63.6%, respectively) than patients with poor PS (2 or 3) and undifferenti-2 Insti
## Background: Low-dose protracted continuous infusion (ci) 5-fluorouracil (5-fu), as proposed by lokich et al, has been reported to be active and well tolerated in colorectal and breast cancers. we initiated a phase ii trial with ci 5-fu in heavily pretreated undifferentiated carcinoma of the naso