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Low density lipoprotein receptor mutations in a selected population of individuals with moderate hypercholesterolemia

✍ Scribed by Marcello Arca; Eero Jokinen


Book ID
119436470
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
308 KB
Volume
136
Category
Article
ISSN
0021-9150

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Mutations of the low density lipoprotein (LDL) receptor in 16 Japanese kindreds with homozygous familial hypercholesterolemia (FH) were studied using an anti-LDL receptor antibody. The LDL receptor mutations in Japanese FH were heterogeneous and included defects in synthesis, post-translational proc