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Characterization of two low density lipoprotein receptor (LDLR) gene mutations in Tunisian familial hypercholesterolemia


Book ID
118631214
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
169 KB
Volume
3
Category
Article
ISSN
1567-5688

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Low density lipoprotein receptor (LDLR)
✍ Jian Wang; Erin Huff; Lenny Janecka; Robert A. Hegele πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 20 KB πŸ‘ 1 views

Heterozygous familial hypercholesterolemia (FH) is a relatively common autosomal dominant disorder, which is characterized by elevated plasma concentrations of low density lipoprotein (LDL) cholesterol and early coronary heart disease. FH results from mutations in the gene encoding the LDL receptor