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Low Activity of β -galactosidase in Frameshift Mutants of Escherichia coli

✍ Scribed by John F. Atkins, Dirk Elseviers and Luigi Gorini

Book ID
123650984
Publisher
National Academy of Sciences
Year
1972
Tongue
English
Weight
723 KB
Volume
69
Category
Article
ISSN
0027-8424

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✍ Bergquist, P. L. ;Truman, Penelope 📂 Article 📅 1978 🏛 Springer 🌐 English ⚖ 304 KB

Ten out of 43 missense mutations in the lacZ gene of Escherchia coli gave rise to polypeptide chains that were degraded in vivo. While many of the mutants appeared to be fully or partially CRM-, there appeared to be no obvious correlation between degradation, map position, altered subunit associatio