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Lovastatin Inhibits Thrombospondin-1-Induced Smooth Muscle Cell Chemotaxis

✍ Scribed by Nowokere Esemuede; Taeseung Lee; Kristopher G. Maier; Bauer E. Sumpio; Vivian Gahtan

Book ID
116706285
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
397 KB
Volume
168
Category
Article
ISSN
0022-4804

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Thrombospondin-1-induced vascular smooth
Thrombospondin-1-induced vascular smooth muscle cell chemotaxis: The role of the type 3 repeat and carboxyl terminal domains
✍ Taeseung Lee; Susan M. Nesselroth; Eric T. Olson; Nowokere Esemuede; Jack Lawler πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 172 KB

## Abstract Thrombospondin‐1 (TSP‐1), an acute phase reactant implicated in vascular disease, is a matricellular glycoprotein with six domains that confer different functions. The authors have shown TSP‐1 induces vascular smooth muscle cell (VSMC) chemotaxis via extracellular signal‐regulated kinas