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Dyslipidemia Regulates Thrombospondin-1–Induced Vascular Smooth Muscle Cell Chemotaxis

✍ Scribed by Kristopher G. Maier; Sufyan A. Siddiqui; Munyaradzi Chimukangara; Thomas Snyder; Keri A. Seymour; Yumna Saeed; Jeffrey J. Stein; Vivian Gahtan

Book ID: 116713203
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 158 KB
Volume: 54
Category: Article
ISSN: 1097-6809
DOI: 10.1016/j.jvs.2011.06.067

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## Abstract Thrombospondin‐1 (TSP‐1), an acute phase reactant implicated in vascular disease, is a matricellular glycoprotein with six domains that confer different functions. The authors have shown TSP‐1 induces vascular smooth muscle cell (VSMC) chemotaxis via extracellular signal‐regulated kinas