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Loss of virulence in Ustilago maydis by Umchs6 gene disruption

✍ Scribed by Ana Garcerá-Teruel; Beatriz Xoconostle-Cázares; Raymundo Rosas-Quijano; Lucila Ortiz; Claudia León-Ramı́rez; Charles A. Specht; Rafael Sentandreu; José Ruiz-Herrera

Book ID: 116860019
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 533 KB
Volume: 155
Category: Article
ISSN: 0923-2508
DOI: 10.1016/j.resmic.2003.11.005

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## Abstract Glioblastoma multiforme (GBM) is the most common and aggressive primary brain tumor and possesses a high incidence of 10p loss. The KLF6 (Kruppel‐like transcription factor) tumor suppressor gene on 10p15 is inactivated by loss of heterozygosity (LOH) and/or somatic mutation in a number