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Loss of one chromosome #13 during development of a polyposis tumor

✍ Scribed by Ragnhild A. Lothe; Tobias Gedde-Dahl; Mette E. Lier; Steinar Aamdahl; Anstein Bergan; Anna E. Stenwig; Anton Broegger

Book ID
119103588
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
670 KB
Volume
28
Category
Article
ISSN
0165-4608

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Molecular nature of chromosome 5q loss i
Molecular nature of chromosome 5q loss in colorectal tumors and desmoids from patients with familial adenomatous polyposis
✍ Mieko Okamoto; Chieko Sato; Yuko Kohno; Takeo Mori; Takeo Iwama; Akira Tonomura; πŸ“‚ Article πŸ“… 1990 πŸ› Springer 🌐 English βš– 600 KB

Familial adenomatous polyposis (FAP), which includes familial polyposis coli (FPC) and the Gardner syndrome (GS), is a genetically determined premalignant disease of the colon inherited by a locus (APC) mapping within 5q15-q22. To elucidate the role of 5q loss in FAP tumorigenesis, we analysed 51 co