✦ LIBER ✦

Loss of normal p53 function confers sensitization to Taxol by increasing G2/M arrest and apoptosis

✍ Scribed by Wahl, Alan F.; Donaldson, Karen L.; Faircnild, Craig; Lee, Frank Y.F.; Foster, Scott A.; Demers, G. William; Galloway, Denise A.

Book ID: 109926736
Publisher: Nature Publishing Group
Year: 1996
Tongue: English
Weight: 1002 KB
Volume: 2
Category: Article
ISSN: 1078-8956
DOI: 10.1038/nm0196-72

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Inactivation of p53 in normal human cell

Inactivation of p53 in normal human cells increases G2/M arrest and sensitivity to DNA-damaging agents

✍ Jocelyn Céraline; Gaël Deplanque; Brigitte Duclos; Jean-Marc Limacher; Amor Hajr 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 French ⚖ 206 KB 👁 2 views

p53 mutations are found in about 70% of human cancers. In order to evaluate the role of these mutations in response to chemotherapeutic agents, it is important to distinguish between p53 response to DNA-damaging agents in normal and in tumour cells. Here, using normal human fibroblasts (NHFs), we sh

Inactivation of p53 in a Human Ovarian C

Inactivation of p53 in a Human Ovarian Cancer Cell Line Increases the Sensitivity to Paclitaxel by Inducing G2/M Arrest and Apoptosis

✍ Faina Vikhanskaya; Sara Vignati; Patrizia Beccaglia; Cristina Ottoboni; Patrizia 📂 Article 📅 1998 🏛 Elsevier Science 🌐 English ⚖ 292 KB

Arsenic trioxide induces apoptosis and G

Arsenic trioxide induces apoptosis and G2/M phase arrest by inducing Cbl to inhibit PI3K/Akt signaling and thereby regulate p53 activation

✍ Yingchun Li; Xiujuan Qu; Jinglei Qu; Ye Zhang; Jing Liu; Yuee Teng; Xuejun Hu; K 📂 Article 📅 2009 🏛 Elsevier Science 🌐 English ⚖ 602 KB

RETRACTED ARTICLE: Cytotoxic activities

RETRACTED ARTICLE: Cytotoxic activities of tubeimoside-2 on human hepatoma HepG2 cells by induction of G2/M phase arrest and apoptosis in a p53-dependent manner

✍ Ying-Yong Zhao; Xu Chao; Yongmin Zhang; Li-Jun Sun; Hong Zhang; Rui-Chao Lin; Xu 📂 Article 📅 2010 🏛 Springer 🌐 English ⚖ 85 KB

Celecoxib leads to G2/M arrest by induct

Celecoxib leads to G2/M arrest by induction of p21 and down-regulation of cyclin B1 expression in a p53-independent manner

✍ Hadas Dvory-Sobol; Efrat Cohen-Noyman; Diana Kazanov; Arie Figer; Shlomo Birkenf 📂 Article 📅 2006 🏛 Elsevier Science 🌐 English ⚖ 232 KB