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Loss of heterozygosity on chromosome 11 in esophageal squamous cell carcinomas

โœ Scribed by Chi Tat Lam; Cecilia Man Ching Tang; Kwok Wai Lau; Maria Li Lung


Book ID
117467211
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
129 KB
Volume
178
Category
Article
ISSN
0304-3835

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## Abstract Allelic loss on chromosome 13 occurs frequently in esophageal squamous cell carcinoma. However, studies of the two known tumor suppressor genes located on 13q, __RB1__ and __BRCA2__, have shown few mutations, suggesting that other genes are likely to be involved in the development of th