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Loss of heterozygosity of the retinoblastoma and adenomatous polyposis susceptibility gene loci and in chromosomes 10p, 10q and 16q in human prostate cancer

✍ Scribed by S. M. A. PHILLIPS; D. G. MORTON; S. J. LEE; D. M. A. WALLACE; J. P. NEOPTOLEMOSH


Book ID
115197626
Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
525 KB
Volume
73
Category
Article
ISSN
1464-4096

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The tumor suppressor gene BRCA1 on chromosome 17q21 has been characterized and shown to be mutated in patients with familial breast and ovarian cancer. Several studies examined the relatives of women with breast cancer and noted an association with ovarian and prostate cancer. This study investigate