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Loss of heterozygosity involving the APC and MCC genetic loci occurs in the majority of human esophageal cancers.

✍ Scribed by Boynton, R. F.; Blount, P. L.; Yin, J.; Brown, V. L.; Huang, Y.; Tong, Y.; McDaniel, T.; Newkirk, C.; Resau, J. H.; Raskind, W. H.


Book ID
121756835
Publisher
National Academy of Sciences
Year
1992
Tongue
English
Weight
880 KB
Volume
89
Category
Article
ISSN
0027-8424

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Loss of heterozygosity at 9p21 loci and
✍ Tatsunori Shimizu; Takao Sekiya πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 French βš– 861 KB

## Abstract To elucidate the involvement of abnormalities of the MTS1/__p16__ and __MTS2/p15__ genes located at chromosomal region 9p21 in human lung cancers, we analyzed DNA from 30 primary lung cancers and detected loss of heterozygosity at the 9p21‐p23 region in 15 tumors. Single‐strand‐conforma