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Loss of heterozygosity at the RB locus correlates with loss of RB protein in primary malignant neuro-endocrine lung carcinomas


Book ID
123277885
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
142 KB
Volume
12
Category
Article
ISSN
0169-5002

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Loss of heterozygosity at the RB locus c
✍ ValΓ©rie Gouyer; Sylvie Gazzeri; Elisabeth Brambilla; Isabelle Bolon; Denis Moro; πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 French βš– 925 KB

## Abstract RB protein expression and loss of heterozygosity (LOH) in the RB gene were studied in 77 primary lung carcinomas of all histological types. RB protein expression was studied by immunohistochemistry with 3 anti‐RB antibodies, and was found altered in 23/29 (79%) neuro‐endocrine (NE) carc