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Loss of heterozygosity at 11p15 and p53 alterations in malignant gliomas

✍ Scribed by Martina Schiebe; Petra Ohneseit; Wolfgang Hoffmann; Richard Meyermann; Hans-Peter Rodemann; Michael Bamberg


Publisher
Springer-Verlag
Year
2001
Tongue
English
Weight
100 KB
Volume
127
Category
Article
ISSN
1432-1335

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Rhabdoid tumors of the kidney are highly malignant neoplasms that occur primarily within the first 3 years of life. Although they are regarded as distinct from Wilms' tumors, their pathogenesis remains unclear. Whereas most cytogenetic studies of these tumors have revealed normal karyotypes, a few r