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Loss of Heterozygosity and Decreased Expression of NME Genes Correlate with Teratomatous Differentiation in Human Male Germ Cell Tumors

✍ Scribed by J.M. Backer; V.V.V.S. Murty; L. Potla; C.E. Mendola; E. Rodriguez; V.E. Reuter; G.G. Bosl; R.S.K. Chaganti


Book ID
115575073
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
407 KB
Volume
202
Category
Article
ISSN
0006-291X

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NM23 is a protein associated with tumor progression, expressed in all tissues and in human tumors. Reduced expression of NM23.H1 is related to high incidence of lymph node and distant metastasis or to poor prognosis of the patient in several human malignant tumors. In this study we analyze NM23 expr