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The differentiation status of primary gonadal germ cell tumors correlates inversely with telomerase activity and the expression level of the gene encoding the catalytic subunit of telomerase

✍ Scribed by Mark Schrader; Angelika M Burger; Markus Müller; Hans Krause; Bernd Straub; Martin Schostak; Wolfgang Schulze; Heidrun Lauke; Kurt Miller

Book ID
115010492
Publisher
BioMed Central
Year
2002
Tongue
English
Weight
387 KB
Volume
2
Category
Article
ISSN
1471-2407

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## BACKGROUND. Telomerase activation is thought to be crucial for the continued growth or progression of cancer cells. Three major subunits of human telomerase, human telomerase RNA (hTR), telomerase-associated protein (TP1), and human telomerase catalytic subunit (hTERT) have been identified rece