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Loss of heterozygosity, a frequent but a non-exclusive mechanism responsible for HLA dysregulation in non-Hodgkin's lymphomas

✍ Scribed by Bernard Drénou; Marcel Tilanus; Gilbert Semana; Mehdi Alizadeh; Brigitte Birebent; Jean-Marc Grosset; Patricia Dias; Dick Van Wichen; Yvonne Arts; Dianne De Santis; Renée Fauchet; Laurence Amiot


Book ID
108672834
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
255 KB
Volume
127
Category
Article
ISSN
0007-1048

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LOSS OF HETEROZYGOSITY AT 5q21 IN NON-SM
✍ COOPER, CINDY A.; BUBB, VIVIEN J.; SMITHSON, NICOLA; CARTER, ROBERT L.; GLEDHILL 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 538 KB

Four genetic poljmorphisms in the AP C and MCC genes at chromosome 5q21 were analysed for loss of heterozygosity &OH) in 97 primary squamous carcinomas and adenocarcinomas of the lung. LOH was identified in at least two polymorphic loci in 41 percent of informative cases. There was no significant di