## Abstract ## Background and Objectives Low tumor expression of the p27^Kip1^ protein, which is involved in cell cycle control and apoptosis, is considered a negative prognostic factor in different types of cancer. The aim of this study was to evaluate the clinical and pathological significance o
Loss of FHIT protein expression correlates with disease progression and poor differentiation in gastric cancer
โ Scribed by Alba Rocco; Laslo Schandl; Jie Chen; Hongbing Wang; Zsolt Tulassay; Deirdre McNamara; Peter Malfertheiner; Matthias P. A. Ebert
- Publisher
- Springer-Verlag
- Year
- 2003
- Tongue
- English
- Weight
- 278 KB
- Volume
- 129
- Category
- Article
- ISSN
- 1432-1335
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## BACKGROUND. The FHIT gene, located at human chromosome 3p14.2, frequently is deleted in a number of human tumors, including breast carcinoma. Its protein product (Fhit) is presumed to have tumor suppressor function. Loss of expression of a tumor suppressor gene is an important step in tumor prog
Expression of CD44 and its variants is associated with clinically aggressive behavior of some human cancers. The present study was undertaken to determine the expression level of these CD44 mRNAs in relation to the clinicopathologic features and prognosis of gastric cancer. Using reverse transcripti