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Loss of Expression of the p16 Gene Is Frequent in Malignant Skin Tumors

✍ Scribed by Ting-Gung Chang; Jyh-seng Wang; Lee-Wei Chen; Ching-Yi Hsu; Hsueh-Wen Chang; Jin-Shyr Chen; Chung-Lung Cho

Book ID
115579588
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
546 KB
Volume
230
Category
Article
ISSN
0006-291X

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Frequent inactivation of the p16 gene in
Frequent inactivation of the p16 gene in human pituitary tumors by gene methylation
✍ Michael Woloschak; Aiqin Yu; Kalmon D. Post πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 87 KB πŸ‘ 2 views

Rodent models of pituitary tumorigenesis have implicated the retinoblastoma (Rb) pathway in the development of pituitary tumors. Previously, we reported that loss of p16 expression rather than loss of Rb occurs in most human pituitary adenomas. This alteration in these tumors is not associated with