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Loss of E-cadherin expression predicts disease recurrence and shorter survival in colorectal carcinoma

✍ Scribed by ADAM ELZAGHEID; ABDELBASET BUHMEIDA; MATTI LAATO; OMRAN EL-FAITORI; KARI SYRJÄNEN; YRJÖ COLLAN; SEPPO PYRHÖNEN


Book ID
114787286
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
502 KB
Volume
120
Category
Article
ISSN
0365-5555

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Previous in vitro and in vivo model studies have shown that when E-cadherin expression in carcinoma cells is reduced, invasive behaviour ensues. The situation in human cancer in vivo, however, appears to be more complex, as immunohistochemically determined E-cadherin expression in various carcinomas