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Loss of DNA sequences on chromosome 3 in renal cell carcinoma

✍ Scribed by W.Marston Linehan; Berton Zbar


Book ID
119046015
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
127 KB
Volume
30
Category
Article
ISSN
0090-4295

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The DNA sequences for Ha-, Ki-, and N-ras were determined in six cell lines derived from independent rat hereditary renal cell carcinomas (RCC). Genomic regions encompassing codons 12, 13, and 61 of Ha-ras, Ki-ras, and N-ras, and codon 117 of Ha-ras were PCR amplified and directly sequenced. The DNA