Gene deletion of chromosome 10 in 11 tumor tissues removed from nine patients with malignant glioma (seven glioblastomas and two malignant astrocytomas) was investigated. Loss of heterozygosity was found in four of the seven (57%) cases with glioblastoma, whereas heterozygosity was preserved in two
Loss of constitutional heterozygosity in human astrocytomas
β Scribed by E. Van de Keift; K. De Boulle; P. Willems; J. -J. Martin; P. Selosse; B. Van der Auwera
- Publisher
- Springer Vienna
- Year
- 1992
- Tongue
- English
- Weight
- 682 KB
- Volume
- 117
- Category
- Article
- ISSN
- 0001-6268
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