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Looking glass inhibitors: both enantiomeric N-benzyl derivatives of 1,4-dideoxy-1,4-imino-d-lyxitol [a potent competitive inhibitor of α-d-galactosidase] and of 1,4-dideoxy-1,4-imino-l-lyxitol [a weak competitive inhibitor of α-d-galactosidase] inhibit naringinase, an α-l-rhamnosidase competitively

✍ Scribed by Thomas B. Mercer; Sarah F. Jenkinson; Barbara Bartholomew; Robert J. Nash; Saori Miyauchi; Atsushi Kato; George W.J. Fleet


Book ID
108284519
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
681 KB
Volume
20
Category
Article
ISSN
0957-4166

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✍ Antonio J. Moreno-Vargas; Inmaculada Robina; Raynald Demange; Pierre Vogel 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 German ⚖ 217 KB 👁 1 views

## Abstract The __García‐González__ reaction of D‐glucose and ethyl acetoacetate generated ethyl 5‐[(1′__S__)‐D‐erythrosyl]‐2‐methyl‐3‐furoate (**5**), which was converted to ethyl 5‐[(1′__R__)‐1′,4′‐dideoxy‐1′,4′‐imino‐D‐erythrosyl]‐2‐methyl‐3‐furoate (**3c**) and to ethyl 5‐[(1′__S__)‐1′,4′‐dideo