Longitudinal genotype analysis and quantification of hepatitis C virus in haemophilia patients receiving interferon-α therapy
✍ Scribed by H. Devereux; P. Telfer; D. Brown; A. Morris; G. Dusheiko; V. Emery; C. Lee
- Book ID
- 115076173
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 426 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1352-0504
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To investigate the relationship between genotypes of hepatitis C virus and response to interferon-a therapy, hepatitis C virus RNA was assayed by polymerase chain reaction with three sets of primers and probes in 70 patients with non-A, non-B chronic hepatitis who received interferon-a. Twenty-four
W e quantified IgG antibodies to structural (core) and nonstructural (C100-3) hepatitis C virus proteins in 42 patients with chronic hepatitis C treated with a 6-mo course of interferon-a. Sera were drawn before and at the end of therapy and also 6 mo after therapy withdrawal; they were stored for l