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Long-term WT1 peptide vaccination for patients with acute myeloid leukemia with minimal residual disease

✍ Scribed by Tsuboi, A; Oka, Y; Kyo, T; Katayama, Y; Elisseeva, O A; Kawakami, M; Nishida, S; Morimoto, S; Murao, A; Nakajima, H; Hosen, N; Oji, Y; Sugiyama, H

Book ID
119980287
Publisher
Nature Publishing Group
Year
2011
Tongue
English
Weight
252 KB
Volume
26
Category
Article
ISSN
0887-6924

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Both WT1 and PRAME are highly expressed in acute myeloid leukemia (AML) patients. To assess the efficacy of their simultaneous detection for the purpose of monitoring minimal residual disease (MRD), we used real-time quantitative RT-PCR to quantify both WT1 and PRAME transcript levels in the bone ma